What is the structure of metronidazole?
C6H9N3O3Metronidazole / Formula
What class of drug is metronidazole?
Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria. Antibiotics will not work for colds, flu, or other viral infections.
What is the Iupac name for metronidazole?
Metronidazole hydrochloride | C6H10ClN3O3 – PubChem.
What are metronidazole drugs?
Metronidazole is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites. This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu).
How is metronidazole metabolized?
Metronidazole is extensively metabolised by the liver to 5 metabolites. The hydroxy metabolite has biological activity of 30 to 65% and a longer elimination half-life than the parent compound.
Is metronidazole broad or narrow spectrum?
Flagyl , known as metronidazole or by the brand name Protostat, is an antibacterial drug that is classified as a broad-spectrum antibiotic. 1 Metronidazole is used to treat certain bacterial infections or protozoal infections (a type of parasite).
Is metronidazole bacteriostatic or bactericidal?
Metronidazole is a bactericidal antibiotic.
What is the mechanism of metronidazole?
Mechanism of Action Metronidazole diffuses into the organism, inhibits protein synthesis by interacting with DNA and causing a loss of helical DNA structure and strand breakage. Therefore, it causes cell death in susceptible organisms.
Is metronidazole broad spectrum?
Is metronidazole a sulfonamide?
Sulfonamides are synthetic, broad-spectrum bacteriostatic antibiotics. Because of associated toxicity and high rates of resistance, their use is now very limited. Metronidazole is the most important member of the 5-nitroimidazole family.
What are the indications of metronidazole?
- Anaerobic Bacterial Infections. Loading dose: 15 mg/kg IV; not to exceed 4 g/day.
- Sexually Transmitted Disease. Prevention following sexual assault.
- Bacterial Vaginosis. Nonpregnant women.
- Colorectal Surgical Infection.
- Giardiasis (Off-label)
- Gardnerella Infection.