Which diabetes medications improve cardiovascular outcomes?
New medications like empagliflozin and liraglutide improve not only CV mortality but also all-cause mortality in diabetic patients with CVD. The FDA has approved specific labels for both empagliflozin and liraglutide to reduce the risk of CV death in adults with diabetes and CVD.
Does sitagliptin have cardiovascular benefits?
Sitagliptin has also been found to reduce cardiac apoptosis, hypertrophy, and fibrosis (5). In addition, DPP-4 inhibitors are considered weight neutral and have generally been shown to improve other cardiovascular risk factors, including low-density lipoprotein, high-density lipoprotein, and blood pressure 6, 7.
Does metformin reduce cardiovascular risk?
Metformin can significantly reduce mortality and reduce the incidence of cardiovascular events, that means metformin can be used as a cardiovascular protective agent to prolong life and reduce mortality.
Which antidiabetic causes heart failure?
Dipeptidylpeptidase 4 inhibitors show an overall neutral outcome, although saxagliptin can possibly be associated with an increased risk of hospitalization for heart failure. The use of sodium-glucose co-transporter 2 inhibitors is associated with beneficial cardiovascular outcomes, and further studies are underway.
What are SGLT2 inhibitor drugs?
SGLT2 inhibitors are a class of prescription medicines that are FDA-approved for use with diet and exercise to lower blood sugar in adults with type 2 diabetes. Medicines in the SGLT2 inhibitor class include canagliflozin, dapagliflozin, and empagliflozin.
What is the difference between Teneligliptin and metformin?
Conclusions: Teneligliptin, a DPP4 inhibitor reduced HbA1C significantly compared with monotherapy of metformin in treatment naive patients at week 12. It also reduced FBG and 2-h PPBG as compared with metformin at week 12.
Which is better glimepiride or Teneligliptin?
Therefore, teneligliptin was generally well tolerated when used in combination with glimepiride. Conclusions: The addition of teneligliptin was effective and generally well tolerated in Japanese patients with T2DM inadequately controlled with glimepiride monotherapy.
What is the difference between Rybelsus and Ozempic?
Rybelsus and Ozempic contain the same active drug, semaglutide, but in different forms. Rybelsus comes as an oral tablet, while Ozempic is given as a subcutaneous injection. Both Rybelsus and Ozempic are brand-name medications. Generic versions of the drugs aren’t currently available.